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pressure3047160301075077120153187234260303 raises336716030107266887119163197 the3581160301072876120 central3718160301074083131158184226245 blood3980160301075069117166216 volume,4213160301074188108155229273288 systemic4518160301073374108137180253272312 venous4847160301074184132180229262 return,512516030107277098146172221237 preload53781603010750771203047174301071967109158 and3224174301074189139 afterload338117430107416596139165185233275324 of3724174301074872 the3815174301072876120 LV.395417430107408192 This4065174301074291110143 is4226174301071952 seen4297174301073378122171 clinically448617430107415978126144185226245264304 as4808174301074175 a49021743010740 subsequent4961174301073481130164208258306350398425 rise540517430107264578122 in3047188301071967 LV3132188301074181 filling3232188301072443628199147196 pressure3447188301075077120153187234260303 and,3769188301074189138154 ultimately,394118830107486795114187228255297317357368 pulmonary4328188301075098117190239287328354397 oedema4744188301074893143187261302 on5064188301074897 CUS51791883010752107147 as5345188301074174 an5438188301074189 increase3047202301071967107134177217250294 in3361202301071967 the3447202301072876121 number3587202301074996170219264291 of3897202301074872 B-Lines3989202301074574116135183227261 [12,4270202101092669109128 38].441720210109469211645312023010716 Limitations30472267015368109213253303366416455519591644 of37122267015363111 CUS38432267015377156223 There3047244301074394140168212 are3287244301074270114 several3429244301073480122167195238258 limitations3715244301071939114134163206235254304355389 related413224430107277192134162206258 to4418244301072877 performing4522244301075198126154203231308328377428 and4978244301074292143 accurately5149244301074284124173201244272317337378 interpreting304725830107196794136163213240283311329377427 CUS.34982583010751107147163 CUS36852583010752107147 is3856258301071952 not3932258301074897124 able4080258301074191110154 to4259258301072774 visualise435725830107416093140181200218251295 deep4676258301074993138188 lung4888258301071966114164 parenchyma5076258301075091118161209249297336410451 and3047272301074189138 mediastinal32082723010774118168187227261290308356397416 structures.364727230107346389138178209257283326360376 The4046272301074292136 inability4205272301071967108157176195213242284 to4512272301072875 detect4610272301074993120163204235 central4868272301074082130157184226245 lesions513627230107196396115163211244 not5403272301074897124 abutting3047286301074293142171203222271322 the3396286301072978124 pleura3547286301075171116165192235 can3810286301074083132 be3970286301075097 particularly4094286301075093120152172213262282324351371412 limiting4534286301071938113133162181230281 in4842286301071969 morbidly49382863010775125153204224275294335 obese53012863010748100146181226 patients3047300301075193121141186235263299 with3373300301076787115165 a35653003010742 thick363430030107297897139178 chest3839300301074190136170200 wall.40673003010766108128147164 Typical4258300301074378130150192234254 limitations4539300301072039114133162205233252302352386 in4952300301071968 the5048300301072878123 intensive519830030107196996140189223242285329 care3047314301074082108151 setting3215314301073377105136154202252 are3483314301074167110 also361031430107416092141 subcutaneous3767314301073481130172219247289337381430478511 emphysema42953143010743117166215254288332405446 and4758314301074189138 extensive4913314301074383114156204237255296340 wound52693143010765113161209258 dressings.3047328301075078122157192211261312346364 A34393283010754 chronic3520328301074291119168218237279 interstitial382732830107196997141169204235255284304346365 disease4220328301075070104150192226272 can4520328301074184134 make46823283010775118157202 interpretation491132830107206997142169221249294323366394414464514 of5453328301074974 the3047342301072876120 CUS31913423010751107147 findings336134230107244391141159207257289 difficult367434230107496791119139179227245273 as3971342301074174 can4068342301074082130 chest4221342301074189133166195 wall44403423010765106125144 deformities4607342301074993117164191266284312331375409 and5039342301074189138 technical5201342301072870111159207226266308327 limitations3047356301071937111129158199226245293341374 [1,344135610109266983 5,3543356101094764 7].362635610109477336983563010716 Conclusion30473807015377142214270309379431471535607 CUS30473983010751110152 is3228398301071955 an3312398301074091 excellent3432398301074486128173195217263314344 tool3805398301072877129151 in3985398301071969 the4083398301072879126 assessment4238398301074177113160196232308355406435 of4702398301074875 various4806398301074185114136187238273 pulmonary51083983010750101122198250301344373419 pathologies3047412301075196127179231254306360383430468 due35474123010750101149 to3729412301072879 the3841412301072880128 fact4002412301072470114148 that4183412301072881125156 there4372412301072880128158205 is4610412301071955 virtually469841230107416494129181225247269313 no50444123010749101 radiation5178412301072773126148192223245297350 involved3047426301071969111161183227273325 and3394426301074192144 it3560426301071849 is3631426301071954 easy3707426301074486122166 to3895426301072777 perform3994426301074997126155205235312 at4328426301074070 the4420426301072879125 bedside.4567426301075097150186206258305322 Especially4911426301074279131178222243286308329372 in5304426301071970 ICU5396426301071973131 patients,3047440301075094124145192243272310328 there3400440301072879126155201 is3625440301071955 a37044403010741 reduction3770440301072672125175218251273323375 in4170440301071869 cumbersome4264440301074090166219266296332384460507 transport4796440301072857102152188240292322355 to5176440301072877 the5278440301072879126 CT5428440301075299 suite3047454301073383104135180 and3249454301074091143 in3414454301071869 suboptimal3505454301073382134186238269290366409430 bedside3957454301075097150185206257304 CXR42834543010751104151 limiting4456454301071940116137168189239291 adequate4769454301074193139191241285314359 diagnosis.5150454301074970113165215266302323358377 An30474683010753104 array3182468301074170100144186 of3399468301074874 pulmonary35054683010749101122198249301344373419 and3955468301074192144 extrapulmonary4130468301074486120149193246297318394445497540569615 pathologies4776468301075094124175226248299352373420456 can5264468301074084135 be5430468301075097 assessed3047482301074177113160196232279332 and3406482301074191143 accurately3576482301074184126176205250280325347389 diagnosed.3992482301074971114166216268304351403422 However,44414823010757108175222265311340354 there4822482301072879126155201 may50504823010773117158 be5235482301075097 limitations53594823010719401161383047496301072872102123174225261 impeding3335496301071995147195248269319372 the3734496301072778125 CUS38864963010752110153 examination,4066496301074386130206227278321351373423475493 especially4586496301074480132180224245288310331374 subcutaneous4987496301073383135179230260304355402454505540 emphysema.30475103010744120172224265302348425468487 In3560510301071969 the3655510301072879126 recent3806510301072772116161212242 COVID-1940735103010751112159182243276317357 atmosphere,4456510301074171147198235286338385414460477 there4958510301072879126155201 is5184510301071954 a52645103010741 huge5330510301074899151197 potential30475243010750102132177228257279322343 for3422524301072374103 CUS35575243010751109152 in3740524301071970 being3841524301075098119170222 used4094524301074883130183 as4308524301074177 a44175243010741 tool4489524301072877129151 in4672524301071869 triage,477252430107285880123175222239 in5042524301071970 indicating5143524301071969121143186230260281332384 invasive3047538301071969112156192213256302 measures,33745383010773120163199249278324360379 in3777538301071969 the3871538301072778125 assessment4021538301074076112159196232308355406435 of4480538301074875 response4579538301072773109161213264300347 to4950538301072877 therapy,5051538301072879126155200252294308 and5383538301074192144 as3047552301074177 a31465523010741 guide3209552301074999120172219 in3450552301071969 mechanical35415523010774121165216259310331374418439 ventilation4003552301074086137166188209252282304354406 setting,4431552301073380111144165216268286 weaning47395523010765111154205226277329 and5090552301074191143 patient5256552301074993123145191242271 positioning.30475663010750102138159189211262313334385437456 Take‑home30475940015377140216275315386450553613 message:368259400153102162216270334399457489 Imaging41945940015340145209273314390453 methods467059400153102161214288352424478 in30476080015338114 severe31846080015351112175235295356 COVID-1935636080015376160241286372412470534 „3093633805637 Chest316463230954688128158185 ultrasound33686323095436085109146176220263306350 (CUS)373863230952165115151172 is393063230951746 the399663230952468107 method4123632309565105130173217262 of440463230954364 first4488632309521396293119 choice462763230953679122139175214 in486063230951760 suspected493963230953072102146186223250289333 severe529263230953069106145169207 COVID-19.316464180954699141161214242276310322 „3093652805637 CUS316465130954695131 becomes331765130954484121163229269299 far36386513095215882 more3742651309565109133171 specific393565130953074114151168190207244 if420065130951738 combined426065130953577143188205248288333 with461465130955875101144 at477965130953761 least48616513095175793123149 basic503165130954482112128164 echocardiography521765130953976119162199236260316466080954460104148172209254298332 protocol.351466080954468110135177214256273288 „3093671805637 Radiographic316467030954178122139183228252289334378395431 methods3618670309566106131175218264293 (CT,393567030952166106116 X-ray)40756703095446590128163183 lack42826703095175490124 sensitivity443067030953070113143160185202239257283321 in477467030951760 the485867030952568108 first4990670309521396393120 48513367030953980 h5237670309543 of530367030954365 the539267030952468108 disease,31646798095446090130166196235248 i.e.3430679809517317184 5-6353267980953963106 days365567980954480115146 after38186798095365886124148 acquisition398467980953672115158175204221246263306350 including43516798095176096113156200217260304 the467367980952468107 incubation47986798095165996138183220245262305348 period.516467980954484108126169214228 „3093690805637 Computed316468930954585150193234259296339 tomography351768930952464129171214237273316358392 (CT)392268930952164103127 is406268930951745 not412068930954284108 indicated424168930951758101117152188212249292 as454668930953665 a4624689309536 default467368930954381102138179196220 diagnostic49066893095435994137179221250275291326 method5245689309564103127169211254 in316469880951760 every324169880953975114138177 patient343569880954482106123163206230 with368269880955876101144 respiratory38446988095236292136154177215239281305344 insufficiency.42056988095176090132154178196232249289332368406417 „3093709805637 Calculation316470830954683100136179196233257274317361 of354270830954264 percentage362370830954484108143181225249286330370 of401070830954264 diseased40917083095436090129165195235280 lung438870830951759102147 parenchyma455270830954481105143187223266301367404 on497370830954286 CT507670830954586 has517970830954379109 a5305708309537 limited535870830951734100117316471780952563108 prognostic328971780954469111156199242272298316352 value36587178095367491133173 and384871780953780124 does399071780954386127157 not416471780954387111 possess429371780954488118148188218248 any455971780953679114 therapeutic469071780952568108132169213254296322339375 implications.508371780951682126144161197234259276319362392407 „3093728805637 Absence316472730954791122161204241279 of346272730954264 significant35457273095294690133150172190226263306330 alveolo-interstitial38947273095365390129173191234260278321345383407438464481507524560577 syndrome449072730953066111155179221287327 on483572730954387 CUS494072730954696132 may5090727309566102137 exclude524672730953975110127169214253 lung31647368095175899142 involvement33207368095165892133150185223287325367390 and372473680953577120 severe385873680952967102140163200 respiratory40727368095236089132148171207231271294332 COVID-19441773680954595134151202228261294 with47247368095577498140 sufficient48777368095307091115132167183221263286 specificity.517673680953072111147163184201236252276313323 „3093747805637 A3164746309547 significant32277463095304791134150172190226263306331 alveolo-interstitial35747463095365390129173191234260278321345384407438464481507524560577 syndrome416874630952966110154178220287326 on451174630954286 CUS461374630954696132 is476174630951746 specific482374630953074115152168190208244 for50837463095216488 COVID-19518974630954598140160214241276310 pneumonitis316475580954488127170236279323340365382412 and359375580953680124 ARDS.373475580954788140177192 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